Skin Lesion Bottleneck from PubMed

Concept Query Document ID Reference Sentence Document Content
Does the lesion appear as irregular dark skin areas with varying color? Malignant Lesion 2696_9916 It is usually described as an irregular dark skin lesion that may have areas of varying colour. ID: 2696_9916, Malignant melanoma (MM) is a malignant tumour, arising from the pigment producing c... View More
Can shiny white streaks be seen on the skin lesion? Malignant Lesion 152_1437 Introduction:Shiny white streaks (SWS) are a new der-moscopic criteria detected under polarized light that have been associated to melanoma and other skin tumours. ID: 152_1437, Finally the lesion was totally extirpated, and based on dermoscopic and histopatholo... View More
Does the skin lesion look melonocytic under dermoscopy? Benign Lesion 201_12776 The concept of an atypical melanocytic lesion (AML) can be applied to any pigmented lesion in which the clinical and dermoscopic criteria are sufficient to classify it as melanocytic... ID: 201_12776, The concept of an atypical melanocytic lesion (AML) can be applied to any pigmented... View More
Are there blood vessels visible in the lesion? Benign Lesion 3589_20537 In addition, many artifacts such as hair strands and blood vessels cause problems during the segmentation. ID: 3589_20537, Dermoscopy allows doctors to diagnose and treat cancerous skin lesions in more det... View More
Does the lesion show characteristics of malignant transformation, such as asymmetry, border irregularity, color variability, diameter of 6 mm or more, rapid growth, shiny and pearly papule, elevated nodule, or telangiectasia? Actinic Keratosis 625_6185 "Skin lesions should be resected for characteristics of malignant transformation, such as asymmetry, border irregularity, color variability, diameter of 6 mm or more, rapid growth, shiny and pearly papule, elevated nodule, or telangiectasia." ID: 625_6185, Patients delay seeking medical care for a number of reasons, including fear of the d... View More
Does the lesion have pigmentation? Basal Cell Carcinoma 2375_12600 They presented with a pigmented lesion that was ultimately diagnosed as a pigmented basal cell carcinoma. ID: 2375_12600, Basal cell carcinoma is the most common skin cancer. Pigmented basal cell carcinom... View More
Does the lesion show signs of arboriform telangiectasias, leaf-like areas, ovoid nests, gray-blue globules or spoke-wheel-areas? Basal Cell Carcinoma 4771_19402 basal-cell carcinoma (arboriform telangiectasias, leaf-like areas, ovoid nests, gray-blue globules, spoke-wheel-areas). ID: 4771_19402, Although in the majority of cases it is common to identify other criteria that aid... View More
Is the lesion asymmetrical? Nevus 1172_8383 The histological criteria currently used in the diagnosis of skin melanocytic lesions consist of the analysis of numerous features, such as: lesion’s asymmetry. ID: 1172_8383, Consequently, in many instances, the diagnosis may be subjective because of differe... View More
Does the lesion have various morphometric features of the epidermis? Nevus 1172_8383 The histological criteria currently used in the diagnosis of skin melanocytic lesions consist of the analysis of numerous features, such as: morphometric features of epidermis. ID: 1172_8383, Consequently, in many instances, the diagnosis may be subjective because of differe... View More
Does the lesion have a whitish rim encircling it? Nevus 2502_16818 Halo nevus (HN) is a rare dermatologic entity characterized by a typical whitish rim encircling the existing melanocytic nevus resembling a halo ID: 2502_16818, Halo nevus (HN) is a rare dermatologic entity characterized by a typical whitish r... View More
Does the lesion have an ill-defined border or irregular margin? Nevus 541_11495 The presence of at least three of the following features led to the clinical diagnosis of an atypical nevus: diameter of at least 5 mm, ill-defined border, irregular margin. ID: 541_11495, The presence of at least three of the following features led to the clinical diagno... View More
Does the lesion show different shades of brown? Nevus 541_11495 The presence of at least three of the following features led to the clinical diagnosis of an atypical nevus: diameter of at least 5 mm, ill-defined border, irregular margin, different shades of brown within the lesion. ID: 541_11495, The presence of at least three of the following features led to the clinical diagno... View More
Does the lesion have a regularly shaped border? Nevus 541_11503 The clinical diagnosis of a congenital nevus was established when a pigmented lesion exhibited at least three of the following criteria: well-defined border. ID: 541_11503, The presence of at least three of the following features led to the clinical diagno... View More
Does the lesion show multiple colors? Seborrheic Keratosis 4771_19415 Seborrheic keratosis can show an irregular structure and multiple colours (dark brown, black, skin coloured, pink, yellow). ID: 4771_19415, Our case confirms the great difficulty in formulating a clinically and dermoscopic... View More
Are there comedo-like openings in the lesion? Seborrheic Keratosis 151_11601 The initial dermoscopic photo demonstrated a cerebriform pattern with comedo-like openings consistent with a seborrheic keratosis. ID: 151_11601, A 69-year-old male with history of invasive melanoma of the left upper arm, melanom... View More
Is the lesion presenting a hyperkeratosis or epidermal hyperplasia? Seborrheic Keratosis 2517_1183 Verrucous nevoid melanoma or seborrheic keratosis-like melanoma is characterized by presenting hyperkeratosis, epidermal hyperplasia and pseudofollicular plugs, resembling a benign lesion. ID: 2517_1183, Verrucous nevoid melanoma or seborrheic keratosis-like melanoma is characterized by... View More
Is there a presence of papillomatous changes in the lesion? Seborrheic Keratosis 430_11907 The histopathological analysis evidenced a conjunctival-covering epithelium with papillomatous changes and irregular acanthosis, at the expense of a proliferation of basaloid cells. ID: 430_11907, Seborrheic keratosis is a benign epithelial neoplasia that occurs mainly in the ski... View More
Does the lesion exhibit multiple pseudohorn cysts containing keratin? Seborrheic Keratosis 430_11907 In addition, the lesion exhibited multiple pseudohorn cysts containing keratin. ID: 430_11907, Seborrheic keratosis is a benign epithelial neoplasia that occurs mainly in the ski... View More
Is there a non-uniform pigmentation or distribution of melanocytes? Solar Lentigo 2290_1454 These include a pagetoid appearance of melanocytes, melanocyte atypia, non-uniform pigmentation/distribution of melanocytes, and increased melanocyte density. ID: 2290_1454, Lentigo maligna (LM) and lentigo-maligna melanoma (LMM) are pigmented skin lesions ... View More
Is there a cobblestone pattern on the skin lesion? Solar Lentigo 4742_24349 nevi with a hyperpigmented structureless pattern on dermatoscopy that display on RCM a cobblestone pattern of the epidermis. ID: 4742_24349, In this editorial, we can only attest to our own impression and experience, as wel... View More
Does the lesion have granular structures? Solar Lentigo 1297_12021 Dermoscopy diagnosis of pigmented macules of the face remains challenging in some cases when lesions share several dermoscopic features, such as brown pseudonetwork and annular granular structures. ID: 1297_12021, Differential diagnosis of pigmented flat lesions of exposed areas comprehends mela... View More
Does the lesion have a central area of ulceration or a rough, crust-like appearance? Squamous Cell Carcinoma 3177_18979 Squamous cell carcinomas often form a central area of ulceration or rough, crust-like appearance. ID: 3177_18979, The skin lesions of metastatic lung cancer do not have a characteristic presentati... View More
Is the lesion rough and hard, with a color darker than normal skin? Squamous Cell Carcinoma 2987_14229 One year after diagnosis, the patient realized that the skin of the abdominal wall was hard and rough without pain, and the color became darker than normal skin. ID: 2987_14229, BACKGROUNDEsophageal cancer is a common cause of cancer-related death worldwide. C... View More
Are there visible skin changes associated with the lesion? Vascular lesion 2234_4067 Minor criteria include organomegaly, extra vascular volume overload, endocrinopathy, skin changes, papilloedema and thrombocytosis or polycythemia. ID: 2234_4067, It is postulated that proinflammatory cytokines especially vascular endothelial gro... View More
Is there a change in the epidermis of the lesion? Melanocytic Nevi 4771_19677 Results showed that OCT could clearly identify important diagnosis elements for melanocytic skin lesions, including the changes in epidermis and the presence and location of the nests of melanocytic cells that make up these lesions. ID: 4771_19677, Up to present however, there are no definitive morphologic diagnostic criteria for... View More
Does this lesion appear elevated? Melanocytic Nevi 541_11502 Elevated lesions showing a papillomatous surface and shades of brown to skin color as well as regular margins were defined as dermal nevi. ID: 541_11502, Hofmann-Wellenhof) for melanocytic nevi, seborrheic keratoses, hemangiomas, dermato... View More
Does the lesion have regular margins? Melanocytic Nevi 541_11502 Elevated lesions showing a papillomatous surface and shades of brown to skin color as well as regular margins were defined as dermal nevi. ID: 541_11502, Hofmann-Wellenhof) for melanocytic nevi, seborrheic keratoses, hemangiomas, dermato... View More
Is the lesion's color uniformly light to dark brown? Melanocytic Nevi 541_11502 Pigmented lesions characterized by a diameter of at least 2 mm, well-defined border, regular margin, uniformly light to dark brown color, and a flat surface were diagnosed as common nevi. ID: 541_11502, Hofmann-Wellenhof) for melanocytic nevi, seborrheic keratoses, hemangiomas, dermato... View More
Is the lesion larger than 2 mm in diameter? Melanocytic Nevi 541_11502 Pigmented lesions characterized by a diameter of at least 2 mm, well-defined border, regular margin, uniformly light to dark brown color, and a flat surface were diagnosed as common nevi. ID: 541_11502, Hofmann-Wellenhof) for melanocytic nevi, seborrheic keratoses, hemangiomas, dermato... View More
Is there a presence of nests of melanocytic cells within the lesion? Melanocytic Nevi 4771_19677 Results showed that OCT could clearly identify important diagnosis elements for melanocytic skin lesions, including the changes in epidermis and the presence and location of the nests of melanocytic cells that make up these lesions. ID: 4771_19677, Up to present however, there are no definitive morphologic diagnostic criteria for... View More
Is the lesion's surface flat? Melanocytic Nevi 541_11502 Pigmented lesions characterized by a diameter of at least 2 mm, well-defined border, regular margin, uniformly light to dark brown color, and a flat surface were diagnosed as common nevi. ID: 541_11502, Hofmann-Wellenhof) for melanocytic nevi, seborrheic keratoses, hemangiomas, dermato... View More
Does the lesion have a darker area within it? Melanocytic Nevi 4771_19275 The specific clonus of melanocytes manifests itself clinically by the darker brown or black area within the nevus. ID: 4771_19275, This study presents a series of eight groups, made up of two lesions each, from di... View More
Is the lesion's surface papillomatous? Melanocytic Nevi 541_11502 Elevated lesions showing a papillomatous surface and shades of brown to skin color as well as regular margins were defined as dermal nevi. ID: 541_11502, Hofmann-Wellenhof) for melanocytic nevi, seborrheic keratoses, hemangiomas, dermato... View More
Does the lesion possess an irregular shape? Does the lesion appear as irregular dark skin areas with varying color? 2564_11829 Brown spots: lesions such as hyperpigmentation, freckles, liver spots, and melasma caused by excess melanin; produce an irregular skin appearance. ID: 2564_11829, The VISIA system provided scoring (number of distinct occurrences of the character... View More
Is the color distribution inside the lesion irregular and uneven? Does the lesion appear as irregular dark skin areas with varying color? 3062_17232 After the feature extraction of the skin lesion area of the segmented image, there are multiple colors presented inside, and the colors are irregular and unevenly distributed. ID: 3062_17232, Pixel-level fusion refers to the fusion of grayscale images and visible light imag... View More
Does the lesion exhibit a blotchy texture? Does the lesion appear as irregular dark skin areas with varying color? 3092_24849 The two main algorithms include the three-step algorithm and the BRAAFF (irregular blotching, parallel ridge pattern, asymmetric structures, asymmetric colors, parallel furrow pattern, and fibrillar pattern) checklist. ID: 3092_24849, 4Acral lentiginous melanoma in a patient with Fitzpatrick skin type VI: variegated... View More
Are shiny white streaks and hypochromic areas visible in the skin lesion? Can shiny white streaks be seen on the skin lesion? 2295_22382 Dermatoscopy found multi-component pattern highlighted by the presence of shiny white streaks and hypochromic area. ID: 2295_22382, Dermatoscopy found multi-component pattern highlighted by the presence of multiple... View More
Does the skin lesion have white radial streaks? Can shiny white streaks be seen on the skin lesion? 3037_4149 There were polymorphic vascular structures and white radial streaks in the lesion. ID: 3037_4149, No obvious signs of damage were seen in the adjacent skull. There were no lesions w... View More
Are patterned white streaks present in the skin lesion? Can shiny white streaks be seen on the skin lesion? 2202_22169 On the mucosa, patterned white streaks may be found. ID: 2202_22169, Diagnosis is based on careful correlation of the clinical, histopathological and i... View More
Is the lesion melanocytic? Does the skin lesion look melonocytic under dermoscopy? 5004_189 In this study we aimed to assess RCM diagnostic accuracy in differentiating between melanocytic and non-melanocytic lesions, when compared to dermoscopy and histological examination. ID: 5004_189, The mosaic formed during RCM imaging allows a direct correlation between dermoscopy ... View More
Are there vascular morphologies present in the lesion? Does the skin lesion look melonocytic under dermoscopy? 2181_25220 Vascular morphology has been identified as an important criteria in dermoscopic diagnosis. ID: 2181_25220, Dermoscopy is a non-invasive technique for diagnosing skin lesions, which aids in ... View More
Does the lesion adhere to the ABCD dermoscopy rule? Does the skin lesion look melonocytic under dermoscopy? 4950_13986 Stolz et al invented the ABCD rule of dermoscopy. ID: 4950_13986, The seminal paper of Pehamberger on pigmented skin lesions pattern analysis, publi... View More
Can the lesion's edges be clearly defined under dermoscopy? Does the skin lesion look melonocytic under dermoscopy? 775_18079 Dermoscopy is very helpful in defining the edge of skin lesions. ID: 775_18079, Composition of different morphological characteristics of skin lesions of the 220 s... View More
Are there morphologic features visible under dermoscopy that are not visible to the naked eye? Does the skin lesion look melonocytic under dermoscopy? 3868_15710 Carli et al. (2004) [1] showed that the examination of a pigmented skin lesion including melanoma using dermoscopy allows physicians to realize morphologic features which are otherwise not visible to the naked eye. ID: 3868_15710, Dermoscopy is a prevalent method used by dermatologists in the diagnosis of melano... View More
Does the lesion lack round structures in dermoscopy? Does the skin lesion look melonocytic under dermoscopy? 3788_7729 The dermoscopy 3PC can easily be employed even by nonexpert dermoscopy users and serve as an additional screening tool when monitoring lesions that return PLA−, especially in lesions that lack round structures in dermoscopy. ID: 3788_7729, There was no significant difference in ABCD criteria or other 3PC criteria between ... View More
Does the lesion display exfoliation or white structureless areas? Are there blood vessels visible in the lesion? 2724_16451 Exfoliation and white structureless areas were observed on the surface of the lesion. ID: 2724_16451, The differential diagnostics of non-pigmented nodular dermatological lesions pose ... View More
Do the lesions contain enlarged blood vessels? Are there blood vessels visible in the lesion? 169_3937 Only small capillaries are visible in the papillary dermis of normal skin, while psoriatic plaques contain enlarged blood vessels. ID: 169_3937, Immunofluorescence detection of VEGFRs in normal, non-lesional, perilesional and les... View More
Are there irregular blood vessels in the lesion? Are there blood vessels visible in the lesion? 2724_16451 The examination demonstrated presence of single, irregular, dot and linear type blood vessels. ID: 2724_16451, The differential diagnostics of non-pigmented nodular dermatological lesions pose ... View More
Are there blood vessels arranged linearly along the lesion? Are there blood vessels visible in the lesion? 852_4364 the satellite lesions were grouped around blood vessels, linearly arranged along the course of the vessels. ID: 852_4364, For benign tumors such as blue nevus, the term “satellite” is used regardless the di... View More
Does the lesion contain dark spots? Are there blood vessels visible in the lesion? 3644_12255 It involves taking bright pictures of the shape of the skin lesion, which comes in the form of dark spots. ID: 3644_12255, The American Center for the Study of Dermatology developed a guide for the possibl... View More
Is there a presence of sharp demarcation in the lesion? Are there blood vessels visible in the lesion? 164_11740 additional dermoscopic criteria, such as fissures, hairpin blood vessels, sharp demarcation. ID: 164_11740, In the vicinity of such globes and blood vessels, we found clusters of apoptotic ce... View More
Does the lesion present with a network of structures? Are there blood vessels visible in the lesion? 164_11740 network-like structures and network structures, which improve diagnostic accuracy. ID: 164_11740, In the vicinity of such globes and blood vessels, we found clusters of apoptotic ce... View More
Does the lesion appear macular (flat) or papular (elevated)? Are there blood vessels visible in the lesion? 2998_20258 The morphology of telangiectatic lesions can be macular (flat) in appearance or more papular (elevated). ID: 2998_20258, Telangiectatic lesions are defined as visible, dilated blood vessels in the skin a... View More
Does the lesion have irregular borders? Does the lesion show characteristics of malignant transformation, such as asymmetry, border irregularity, color variability, diameter of 6 mm or more, rapid growth, shiny and pearly papule, elevated nodule, or telangiectasia? 978_13416 Border irregularity refers to the blurring, notching, or unevenness of the lesion's border. ID: 978_13416, Current methods of melanoma diagnosis Clinical Markers The first step in melanoma d... View More
Does the color of the lesion vary or change? Does the lesion show characteristics of malignant transformation, such as asymmetry, border irregularity, color variability, diameter of 6 mm or more, rapid growth, shiny and pearly papule, elevated nodule, or telangiectasia? 978_13416 Color variability/change refers to the lesion having a range of colors, such as various hues of brown or black, or gradually becoming darker or paler. ID: 978_13416, Current methods of melanoma diagnosis Clinical Markers The first step in melanoma d... View More
Does the lesion appear as an elevated nodule? Does the lesion show characteristics of malignant transformation, such as asymmetry, border irregularity, color variability, diameter of 6 mm or more, rapid growth, shiny and pearly papule, elevated nodule, or telangiectasia? 978_13416 Asymmetry refers to the irregularity in the lesion's shape, in which one half differs from the other. ID: 978_13416, Current methods of melanoma diagnosis Clinical Markers The first step in melanoma d... View More
Does the skin lesion show abnormal pigmentation network? Does the lesion have pigmentation? 210_6295 The validation of two triage algorithms, the Three-Point Checklist (asymmetry, atypical network, blue-white color)... ID: 210_6295, Triage in the context of skin lesion evaluations requires the examiner to determine ... View More
Is the pigmentation of the lesion uniform? Does the lesion have pigmentation? 4785_31883 For trunk and extremities, the more common melanoma-specific criteria include multi-component pattern and atypical pigment networks. ID: 4785_31883, For trunk and extremities, the more common melanoma-specific criteria include mult... View More
Is the lesion blue or white in color? Does the lesion have pigmentation? 210_6295 The validation of two triage algorithms, the Three-Point Checklist (asymmetry, atypical network, blue-white color)... ID: 210_6295, Triage in the context of skin lesion evaluations requires the examiner to determine ... View More
Are there pigmented structures in the lesion? Does the lesion have pigmentation? 2691_26908 However, BCC lesions often prove difficult to diagnose due to the lack of pigmented structures. ID: 2691_26908, Hence, investigation of vascular structures in skin lesions using non-invasive tec... View More
Does the lesion exhibit any vascular structures? Does the lesion have pigmentation? 2691_26908 Thus, detection and quantification of lesion vasculature may provide critical information for diagnosis and prognosis. ID: 2691_26908, Hence, investigation of vascular structures in skin lesions using non-invasive tec... View More
Does the lesion have a multi-component pattern? Does the lesion have pigmentation? 4785_31883 For trunk and extremities, the more common melanoma-specific criteria include multi-component pattern. ID: 4785_31883, For trunk and extremities, the more common melanoma-specific criteria include mult... View More
Are tree-like vessels present in the lesion? Does the lesion have pigmentation? 152_1314 Tree like vessels were only seen in BCC lesions. ID: 152_1314, It has been applied in the diagnosis of skin tumors such as Basal cell carcinoma (BC... View More
Does the lesion display arborizing telangiectasias? Does the lesion show signs of arboriform telangiectasias, leaf-like areas, ovoid nests, gray-blue globules or spoke-wheel-areas? 5356_33567 Diagnosis of pigmented BCC is based on the absence of a pigmented network and the presence of at least one of the following criteria: multiple bluegray globules; leaf-like areas; spoke-wheel areas; large, blue-gray ovoid nests; ulcerations; and arborizing telangiectasias. ID: 5356_33567, Several of these devices also have contact dermoscopy capabilities in an attempt t... View More
Does the lesion show any signs of ovoid nests? Does the lesion show signs of arboriform telangiectasias, leaf-like areas, ovoid nests, gray-blue globules or spoke-wheel-areas? 2515_20524 We analyzed the following dermatoscopic features of BCC according to the criteria of Menzies et al.9 and Altamura et al.10: (1) classic BCC patterns including large blue-gray ovoid nests. ID: 2515_20524, We analyzed the following dermatoscopic features of BCC according to the criteria ... View More
Does the lesion exhibit irregular prominence of pigmentation? Is the lesion asymmetrical? 4109_10311 These include(i) hyperpigmentation: skin colour that is darker than normal. ID: 4109_10311, Thus, the number of colours present in a lesion can also help differentiate many b... View More
Does the lesion exhibit a range of sizes and shapes? Is the lesion asymmetrical? 3038_15656 a polymorphic variant with larger lesions of variable size and shape, which is typically seen in children. ID: 3038_15656, The term urticaria pigmentosa was coined by Sangster in 1878 to describe skin lesi... View More
Does the lesion appear erythematous? Does the lesion have various morphometric features of the epidermis? 5336_15820 On physical examination, large erythematous, superficial, crusted erosions were noted on both axillae. ID: 5336_15820, The patient had been previously diagnosed as having chronic eczema and treated wit... View More
Are there short, thin and slightly curved vessels around the lesion? Does the lesion have a whitish rim encircling it? 4742_24272 Finally, dermoscopy of healed lesions revealed a whitish structureless center surrounded by a rim of short, thin and slightly curved vessels. ID: 4742_24272, Finally, dermoscopy of healed lesions revealed a whitish structureless center surr... View More
Is the lesion surrounded by a rim of brownish pigmentation? Does the lesion have a whitish rim encircling it? 210_5080 Dermoscopy demonstrated a whitish-yellow structureless area over entire lesion surrounded by a rim of brownish pigmentation. ID: 210_5080, Detailed examination revealed multiple slightly erythematous to skin-colored infiltr... View More
Does the lesion have color variegation? Does the lesion have an ill-defined border or irregular margin? 4765_4335 the lesions showed malignant properties, such as color variegation and ill-defined border ID: 4765_4335, Although the clinical diagnosis of the black macules was divided nevus of the penis... View More
Does the lesion have well-defined borders? Does the lesion have an ill-defined border or irregular margin? 4443_19915 Lesions in tuberculoid leprosy are usually scanty and symmetrical with smooth borders ID: 4443_19915, Lesions in tuberculoid leprosy are usually scanty and symmetrical with smooth bord... View More
Are the lesion borders diffuse and ill-defined? Does the lesion have an ill-defined border or irregular margin? 2896_10968 In mandibular xanthoma, the radiographic appearance varies widely, from lesions with well-defined sclerotic margins to lesions with diffuse and ill-defined borders ID: 2896_10968, In the present case, histopathological examination showed sheets of foamy and non-... View More
Does the lesion show diffuse pigmentation of different shades of brown colour? Does the lesion show different shades of brown? 4771_19570 Diffuse pigmentation of different shades of brown colour not respecting furrows or ridges was observed. ID: 4771_19570, Detailed examination revealed a suspicious, dark brown 8 mm lesion located on the ... View More
Is the border of the lesion raised? Does the lesion have a regularly shaped border? 4323_28501 These lesions usually start in infancy or childhood and consist of erythematous or purpuric edematous lesions, often with annular shape with raised borders and a flat, purpuric center. ID: 4323_28501, The skin lesions of CANDLE syndrome are very characteristic and should raise the d... View More
Is the lesion's border complex or simple? Does the lesion have a regularly shaped border? 1155_23798 Fractal dimension is a mathematical parameter that is able to quantify the irregularity of a skin lesion border via an objective observer-independent value, such that a higher fractal dimension refers to a higher degree of complexity of the analyzed pattern. ID: 1155_23798, Fractal dimension has been used in characterizing skin lesion border irregularity ... View More
Does the lesion differ from a convex object? Does the lesion have a regularly shaped border? 1155_23800 Convex objects tend to have a convexity value of 1, as opposed to non-convex objects (i.e., irregular skin lesion borders) which tend to be less than 1. ID: 1155_23800, As melanoma borders tend to be irregular they are considered to be similar to frac... View More
Does the border of the lesion have a round shape? Does the lesion have a regularly shaped border? 1557_40407 A typical CL ulcerated lesion is characterized by a round shape and raised borders associated with regional adenopathy. ID: 1557_40407, The criteria used for the diagnosis of CL were the presence of a typical ulcerated... View More
Is the lesion larger in diameter or darker in color? Does the lesion show multiple colors? 3665_15803 D (Di-ameter/Dark) represents that the melanoma lesions are more extensive and exhibit darker shades. ID: 3665_15803, The primary skin examination known as the ABCDE rule should be applied to identify... View More
Does the lesion have uneven or notched borders? Does the lesion show multiple colors? 3665_15803 B (Border) says that most of the melanoma exhibit uneven surface and notched borders. ID: 3665_15803, The primary skin examination known as the ABCDE rule should be applied to identify... View More
Does the lesion have a smooth, dome-shape? Does the lesion show multiple colors? 3475_10371 In general, skin lesions appear as multiple, white-to-flesh colored, smooth, dome-shaped papules. ID: 3475_10371, In other words, lung involvement in BHD does not bring about the progressive decli... View More
Are there milia-like cysts in the lesion? Are there comedo-like openings in the lesion? 4771_19554 Dermoscopic criteria for the diagnosis of clonal SK have recently been described. They include the presence of blue globules and milia-like cysts in the context of a sharply demarcated lesion. ID: 4771_19554, Dermoscopy was performed next, revealing the presence of blue-gray ovoid globules,... View More
Does the lesion contain a dark brown-colored keratin plug? Are there comedo-like openings in the lesion? 1999_17929 Dermoscopic findings showed multiple, round- to oval-shaped, comedo-like openings; a central, dark brown-colored keratin plug. ID: 1999_17929, Physical examination revealed localized, grouped, pin-head-sized, black-colored, c... View More
Does the lesion present with a black or brown coloration on the surface? Are there comedo-like openings in the lesion? 2195_12506 In this case, the skin surface is open and the comedo has a dark appearance, with black or brown coloration on the surface. ID: 2195_12506, The closed comedo is characterized by sebum and skin cells blocking the opening of... View More
Does the lesion have a reticulated network with a central hyperpigmented area? Are there comedo-like openings in the lesion? 151_11598 On dermoscopic exam the lesion was noted to have a reticulated network with a central hyperpigmented area. ID: 151_11598, A 46-year-old female with history of dysplastic nevi, no personal history of melano... View More
Does the lesion present with hyperkeratosis? Is the lesion presenting a hyperkeratosis or epidermal hyperplasia? 2165_32698 Psoriatic lesions are mainly characterized by hyperkeratosis and epidermal hyperplasia. ID: 2165_32698, Psoriatic lesions are mainly characterized by hyperkeratosis and epidermal hyperpl... View More
Can brownish-black verrucose plaques be seen on the body? Is the lesion presenting a hyperkeratosis or epidermal hyperplasia? 2001_13689 A 2-year-old girl presented with large, hairless, yellowish-brown plaques on the scalp and face along with multiple brownish-black verrucose plaques and brownish-black macules on almost all parts of the body. ID: 2001_13689, Epidermal nevus syndromes are a group of rare multiorgan disorders. Schimmelpennin... View More
Do you observe a dry, thick, irregular, and rough surface on the lesion? Is the lesion presenting a hyperkeratosis or epidermal hyperplasia? 355_6853 Gross lesions on the pawpads or nasal planum include a dry, thick, irregular, and rough surface in which crusts, fissures, or erosions can develop. ID: 355_6853, In some cases an underlying cause is not determined; thus the condition is considere... View More
Does the lesion have a central keratin plug? Is there a presence of papillomatous changes in the lesion? 15_13924 On dermoscopy, we observed a central keratin plug, covering a papillomatous lesion. ID: 15_13924, A 42-year-old man attended the skin cancer unit seeking medical advice for a verruco... View More
Does the lesion have atypical linear vessels? Is there a presence of papillomatous changes in the lesion? 15_13924 Atypical linear vessels transcended the papillomatous projections. ID: 15_13924, A 42-year-old man attended the skin cancer unit seeking medical advice for a verruco... View More
Does the lesion exhibit papillomatosis? Does the lesion exhibit multiple pseudohorn cysts containing keratin? 2550_10488 The lesion exhibited papillomatosis ID: 2550_10488, On palpation, the mass was firm in consistency with no tenderness or discharge.Fig... View More
Are there pseudohorn cysts in the lesion? Does the lesion exhibit multiple pseudohorn cysts containing keratin? 430_11909 In addition, the lesion itself exhibited multiple keratin-containing pseudohorn cysts ID: 430_11909, Both eyes had an intraocular pressure of 9 mmHg. Slit-lamp biomicroscopy revealed a... View More
Does the lesion display a papillomatous surface? Does the lesion exhibit multiple pseudohorn cysts containing keratin? 878_4001 these dermoscopic characteristics correspond to papillomatous surface of the epidermis ID: 878_4001, Histopathologically, these dermoscopic characteristics correspond to luminal opening... View More
Are there multiple follicular comedo-like openings on the lesion? Does the lesion exhibit multiple pseudohorn cysts containing keratin? 2559_8535 This appearance grossly corresponds to the multiple intraluminal layers of keratin within the cyst ID: 2559_8535, Folliculocystic and collagen hamartoma is newly described as a term for a complex h... View More
Does the lesion have a greyish blue veil? Is there a non-uniform pigmentation or distribution of melanocytes? 152_1447 Dermoscopy revealed arborizing vessels, ovoid nests, specific for pigmented basal cell carcinoma, and a greyish blue veil. ID: 152_1447, Der-moscopy revealed arborizing vessels, ovoid nests, specific for pigmented basal c... View More
Does the lesion have a non-continuous discoloration? Is there a non-uniform pigmentation or distribution of melanocytes? 4763_7542 A first step is dedicated to the differentiation of a melanocytic origin (longitudinal melanonychia) from a non-melanocytic origin of the nail pigmentation. ID: 4763_7542, The clinical and dermatoscopic evaluation of nail alterations is often a diagnostic... View More
Does the pigmented skin lesion exhibit a pigment network or brown globules? Is there a non-uniform pigmentation or distribution of melanocytes? 152_10187 Only 13 melanocytic lesions (7.5%) were incorrectly classified as non-melanocytic because of the absence of a pigment network or brown globules. ID: 152_10187, Only 13 melanocytic lesions (7.5%) were incorrectly classified as non-melanocytic b... View More
Does the lesion exhibit equal and symmetrical distribution of black dots and globules in the area of the brown pigmentation? Is there a non-uniform pigmentation or distribution of melanocytes? 4746_10162 However, dermoscopic patterns of the present case, including the equal and symmetrical distribution of black dots and globules in the area of the brown pigmentation, are different from the patterns of malignant melanoma on acral volar skin. ID: 4746_10162, Thus, pigmented Spitz nevus on the sole of the foot may be a differential diagnosi... View More
Does the lesion have multiple large round cells? Is there a cobblestone pattern on the skin lesion? 1917_23371 Lentigo maligna...multiple large round pagetoid cells and large nucleated cells in dermis. ID: 1917_23371, Reflectance confocal microscopy is a novel non-invasive diagnostic technique based... View More
Are there dense and sparse nests of cells in the lesion? Is there a cobblestone pattern on the skin lesion? 1917_23371 Similarly, dermoepidermal junctions are disorganized and the dermis has dense and sparse nests of cells. ID: 1917_23371, Reflectance confocal microscopy is a novel non-invasive diagnostic technique based... View More
Is the lesion characterized by a yellow color? Is there a cobblestone pattern on the skin lesion? 1483_7407 The patient presented two of these major criteria: characteristic yellow cobblestone lesion in the skin. ID: 1483_7407, PXE is a rare inherited disorder, characterised by mineralization disturbances of t... View More
Does the skin lesion show a uniform globular pattern? Is there a cobblestone pattern on the skin lesion? 2502_16841 The most common overall dermoscopic patterns were the uniform globular pattern. ID: 2502_16841, The most common overall dermoscopic patterns (presented also in Table 1) were the ... View More
Are there blue granules identified in the lesion? Is there a cobblestone pattern on the skin lesion? 2502_16841 Blue granules and/or with scar-like areas with pattern coexisted in some lesions. ID: 2502_16841, The most common overall dermoscopic patterns (presented also in Table 1) were the ... View More
Does the lesion present as a flat pigmented area? Does the lesion have granular structures? 170_5190 Especially in the context of early lesions, clinical characteristics can be insufficient to allow differentiation among these entities, since they all present as flat pigmented lesions typically developing on sun-damaged skin of elderly individuals. ID: 170_5190, Especially in the context of early lesions, clinical characteristics can be insuffic... View More
Does the lesion have pigmented folicles? Does the lesion have granular structures? 170_5190 The traditional dermoscopic criteria of LM include asymmetrically pigmented follicles, circle within the circle, annular-granular pattern, rhomboidal structures, obliteration of the hair follicles and gray pseudo-network. ID: 170_5190, Especially in the context of early lesions, clinical characteristics can be insuffic... View More
Is the border of the lesion irregular? Does the lesion have granular structures? 14_21003 Lastly, Carbone et al [2] developed a scoring system to improve the diagnosis of LM with 7 dermatoscopic criteria: HFO, rhomboidal structures, target-like pattern, perifollicular gray color, dark blotches, moth-eaten border, and fingerprint-like structures. ID: 14_21003, Lastly, Carbone et al [2] developed a scoring system to improve the diagnosis of LM ... View More
Does the lesion have a crust-like appearance? Does the lesion have a central area of ulceration or a rough, crust-like appearance? 3314_3560 The lesions appeared predominantly in the genital area as whitish-coloured lesions, which evolved with the formation of a central crust. ID: 3314_3560, On 3 May 2022, five males with atypical skin ulcerative lesions with similar body d... View More
Is the lesion characterized by a rough or raised edge? Does the lesion have a central area of ulceration or a rough, crust-like appearance? 1164_15896 The central area of the lesion was depressed and the peripheral edge of the lesion rose above the normal edge of the skin. ID: 1164_15896, Attempts were made to collect worms surgically from the subcutis of the immobilize... View More
Is the lesion accompanied by erythema (redness)? Does the lesion have a central area of ulceration or a rough, crust-like appearance? 819_15080 The NC group had ulcerations without defined borders, intense edema, erythema, and crust appearance. ID: 819_15080, No clinical signs of toxicity were observed in animals receiving the treatments. Th... View More
Does the lesion appear as a nodule? Does the lesion have a central area of ulceration or a rough, crust-like appearance? 2679_24175 In the nodular type, the clinical expression is that of fibrotic, erythematous-violaceous nodules with a smooth or hyperkeratotic surface. ID: 2679_24175, In the nodular type, the clinical expression is that of fibrotic, erythematous-vio... View More
Is the skin around the lesion rough without pain? Is the lesion rough and hard, with a color darker than normal skin? 2987_14232 the skin of the abdominal wall was hard and rough without pain ID: 2987_14232, In this case report, we describe an 82-year-old male who was diagnosed with esopha... View More
Does the lesion appear as a rough or scaly papule or plaque? Is the lesion rough and hard, with a color darker than normal skin? 2350_15976 Pigmented actinic keratoses present as papules or plaques that are rough or scaly ID: 2350_15976, They observed four patients who demonstrated spreading lesions that similarly vari... View More
Does the lesion appear red and scaly? Are there visible skin changes associated with the lesion? 4207_13206 Cutaneous LE diagnosis was based on clinical criteria of discoid LE (red, scaly patches of variable size, which heal with atrophy, scarring, and pigmentary changes) ID: 4207_13206, Cutaneous LE diagnosis was based on clinical criteria of discoid LE (red, scaly pa... View More
Is the lesion located on the extremities? Are there visible skin changes associated with the lesion? 1860_15414 location of the lesion on the extremities ID: 1860_15414, Clinical characteristics associated with isolation of Borrelia burgdorferi sensu l... View More
Is the lesion several centimeters in size? Does this lesion appear elevated? 3145_20727 Plaques are usually several centimeters in size. ID: 3145_20727, To establish the diagnosis of Sweet's syndrome, two major criteria comprising char... View More
Are there multiple lesions? Does this lesion appear elevated? 3145_20727 Multiple lesions appear predominantly. ID: 3145_20727, To establish the diagnosis of Sweet's syndrome, two major criteria comprising char... View More
Are there any visually identifiable vessels associated with the lesion? Does the lesion have regular margins? 5356_33569 Finally, hairpin vessels are most closely correlated with seborrheic keratoses, but can also be observed in SCC. ID: 5356_33569, Finally, hairpin vessels are most closely correlated with seborrheic keratoses, bu... View More
Is the lesion surrounded by an erythematous halo? Does the lesion have regular margins? 4936_20133 For recurrent aphthous stomatitis, oral ulcers (aphthae) are surrounded by an erythematous halo. ID: 4936_20133, The clinician should be able to distinguish the lesions of PV from those caused by... View More
Does the lesion display symptoms of superficial tumor-related telangiectasias? Does the lesion have regular margins? 5356_33569 Superficial tumor-related telangiectasias are often difficult to distinguish on photodamaged skin with actinic lesions. ID: 5356_33569, Finally, hairpin vessels are most closely correlated with seborrheic keratoses, bu... View More
Are there any gray-brown to gray-white areas in the lesion? Is the lesion's color uniformly light to dark brown? 159_4829 Dermoscopy showed a light-to-dark brown homogenous-reticular pattern with focal gray-brown to gray-white areas. ID: 159_4829, A 67-year-old man was referred to our department because of a pigmented skin lesion ... View More
Can the lesion color be classified into categories: normal, light brown, brown, and dark brown? Is the lesion's color uniformly light to dark brown? 4297_5827 Color of the skin lesion: Score 0: normal color; 1: light brown; 2: brown; 3: dark brown. ID: 4297_5827, The area and color of the skin lesion combined with the clinical condition were tak... View More
Is the lesion smaller than 5 mm in diameter? Is the lesion larger than 2 mm in diameter? 2884_3438 If the fibrils composing the FP is thick and regular in color, the lesion is certainly diagnosed as acral nevus, particularly when the lesion is small, ie, less than 5 mm in diameter. ID: 2884_3438, In our case series, this “regular” FP was observed in 2 out of 10 lesions of AM in ... View More
Are the melanocytic cells arranged in nests? Is there a presence of nests of melanocytic cells within the lesion? 1172_8380 Nevus cells, arising as a result of proliferation of melanocytes at the dermal-epidermal junction, are larger than typical melanocytes, do not have dendrites, have more abundant cytoplasm with coarse granules, and are typically grouped in nests. ID: 1172_8380, Skin melanocytic lesions are neoplasms derived from epidermal melanocytes. The two ... View More
Does the lesion have a flat surface? Is the lesion's surface flat? 333_5666 EM is raised and palpable, whereas SJS/TEN lesions are flat. ID: 333_5666, The study also showed that skilled pathologists were unable to distinguish EM from S... View More
Is the surface of the lesion granular or uneven? Is the lesion's surface flat? 1908_8255 If the tumor with a granular or uneven surface was more than 1 cm in size for an elevated lesion... ID: 1908_8255, Therefore, the size of the submucosal invasion was set differently according to ele... View More
Does the lesion appear as raised nodules, slightly elevated, or flat? Is the lesion's surface flat? 2380_9287 Stage 1 is labeled Mild KS, with disease limited to skin, flat oral mucosa lesions, and/or flesh colored subcutaneous nodules, with fewer than 10 lesions total. ID: 2380_9287, Stage 1 is labeled Mild KS, with disease limited to skin, flat oral mucosa lesions,... View More
Is the lesion scar flat and lacks hyperplasia? Is the lesion's surface flat? 741_19977 The skin in the surgical area was soft with flat scars and no evidence of hyperplasia. ID: 741_19977, Through pathological diagnosis, intradermal nevi were identified in the specimens r... View More
Does the lesion have a visibly smooth and even surface? Is the lesion's surface flat? 1908_8263 The novel endoscopic criteria for T staging in SESC were as follows: I. flat or slightly elevated or depressed lesion with smooth/even surface of any size. ID: 1908_8263, In other words, if the tumor with a granular or uneven surface was more than 1 cm i... View More
Does the lesion have a darker center? Does the lesion have a darker area within it? 5255_24353 The initial skin lesions are usually poorly defined macules with darker purpuric centers that coalesce. ID: 5255_24353, Typically, the initial presentation is marked by symptoms of fever, myalgia, and g... View More
Is the lesion larger than usual at the time of diagnosis? Does the lesion have a darker area within it? 3434_12738 The most common high-risk feature was increased clinical lesion size at the time of diagnosis. ID: 3434_12738, There was a high proportion of other high-risk features among pigmented BCCs in th... View More
Is the lesion gray to brown in color? Is the lesion's surface papillomatous? 4762_23205 presented with multiple, small, well- defined, gray-brown, papules. ID: 4762_23205, A 54 year-old-man, presented with multiple, small, well- defined, gray-brown, papu... View More
Is the lesion presenting as a verrucous surface? Is the lesion's surface papillomatous? 2906_17496 slowly growing large exophytic lesions with a papillomatous or verrucous surface. ID: 2906_17496, It is associated with dyspigmentation (usually hyperpigmentation) and an increase ... View More
Does the lesion exhibit dyspigmentation? Is the lesion's surface papillomatous? 2906_17496 It is associated with dyspigmentation (usually hyperpigmentation). ID: 2906_17496, It is associated with dyspigmentation (usually hyperpigmentation) and an increase ... View More
Is the lesion round to oval in shape? Is the lesion's surface papillomatous? 355_6767 Early gross lesions are well-circumscribed, round to oval, red plaques up to 6 cm in diameter. ID: 355_6767, The cause of papillomatous digital dermatitis is multifactorial and likely involves ... View More
Is the lesion irregular in shape? Does the lesion possess an irregular shape? 2538_10942 CLE criteria for cancer/HGIN lesions were irregularity in glandular size and shape. ID: 2538_10942, CLE criteria for cancer/HGIN lesions were irregularity in glandular size and shape... View More
Do the lesions present as patches with an irregular shape? Does the lesion possess an irregular shape? 1286_27116 Frieden and Schierz reported that lesions that are non inflammatory, well demarcated, sheet-like, or appear as patches with irregular shapes. ID: 1286_27116, Aplasia cutis congenita is primarily a clinical diagnosis with no specific histolo... View More
Does the lesion show atypical pigment network? Is the color distribution inside the lesion irregular and uneven? 519_33381 Dermoscopic examination demonstrated atypical pigment network with small dotted vessels. ID: 519_33381, A 89-year-old Japanese woman presented at our clinic because of a several months’ h... View More
Does the lesion have uneven thickness? Is the color distribution inside the lesion irregular and uneven? 2986_26115 The malignant lesions were irregular in shape, with radial enhancement on the edge, uneven thickness. ID: 2986_26115, Conventional color Doppler ultrasound can detect the nutrient vessels with a diame... View More
Is there a rough surface on the lesion? Is the color distribution inside the lesion irregular and uneven? 519_33381 Physical examination revealed a single hyperpigmented oval macule of 5 mm with a rough surface. ID: 519_33381, A 89-year-old Japanese woman presented at our clinic because of a several months’ h... View More
Does the lesion have an unclear boundary? Is the color distribution inside the lesion irregular and uneven? 3100_12989 The edges were relative clear, with the low halo surrounded. ID: 3100_12989, The characteristics of two-dimensional ultrasound imaging of primary hepatic carci... View More
Does the lesion present with irregular streaks? Is the color distribution inside the lesion irregular and uneven? 519_33381 Irregular streaks were also partially noted at the periphery. ID: 519_33381, A 89-year-old Japanese woman presented at our clinic because of a several months’ h... View More
Does the lesion show irregular globular patterns? Is the color distribution inside the lesion irregular and uneven? 2934_12778 Dermoscopic findings are irregular globular pattern, atypical vessels and/or irregular dots/globules. ID: 2934_12778, 1-6Clinical features are aspecific; dermoscopic findings are irregular globular pa... View More
Does the lesion have an asymmetric disposition? Is the color distribution inside the lesion irregular and uneven? 2934_12778 Asymmetry of the lesion and pigment distribution, predominance of irregular nests with varying size and shape, presence of dentritic melanocytes in the epidermis, focal pagetoid spread and mitoses. ID: 2934_12778, 1-6Clinical features are aspecific; dermoscopic findings are irregular globular pa... View More
Is the lesion hyperpigmented? Does the lesion exhibit a blotchy texture? 3393_841 On local skin examination, the lesions were bilaterally and symmetrically hyperpigmented patches on the upper back. ID: 3393_841, Body, hair, nails, and mucous membrane examinations were normal, and the patient had... View More
Is the lesion texture varied? Does the lesion exhibit a blotchy texture? 2969_6440 The feature extraction consists of the existing and novel color and texture attributes measuring how color and texture vary inside the lesion. ID: 2969_6440, AbstractPurposeMelanoma is known as the most aggressive form of skin cancer and one... View More
Does the lesion show dry scaly areas? Does the lesion exhibit a blotchy texture? 3858_3105 In progressed lesions; rough, scaly areas are developed in a drier portion of the vermilion. ID: 3858_3105, Actinic Keratosis: The lesion is a common cutaneous premalignant caused by cumulati... View More
Does the lesion exhibit increased skin texture? Does the lesion exhibit a blotchy texture? 3903_7807 Calluses, corns, xerotic heel skin and heel fissures had significantly lower levels of hydration; less elasticity and greater surface texture than unaffected skin sites. ID: 3903_7807, BackgroundPlantar foot skin exhibits unique biophysical properties that are distinc... View More
Is there evidence of hypochromic areas within the skin lesion? Are shiny white streaks and hypochromic areas visible in the skin lesion? 4409_10439 Physical examination revealed anesthetic distal phalangeal atrophy associated with hypochromic, anesthetic macular lesions. ID: 4409_10439, Physical examination revealed anesthetic distal phalangeal atrophy associated with... View More
Is the lesion center reddish or white? Does the skin lesion have white radial streaks? 3037_4159 Its center was reddish or white ID: 3037_4159, Dermatoscopy showed that the skin lesion was lobular and crumby. The lesion center ... View More
Is the surface of the lesion granular and papillary? Does the skin lesion have white radial streaks? 3037_4143 The surface of the lesion was bright red, granular, and papillary ID: 3037_4143, In this study, a 35-day-old girl was admitted to Kunming Children’s Hospital in Oct... View More
Can polymorphic vascular structures be seen in the lesion? Does the skin lesion have white radial streaks? 3037_4140 There were polymorphic vascular structures and white radial streaks in the lesion ID: 3037_4140, BACKGROUNDSyringocystadenoma papilliferum (SCAP) represents a rare, noncancerous ad... View More
Are there vascular clusters scattered in the lesion? Does the skin lesion have white radial streaks? 3037_4159 with some vascular clusters scattered ID: 3037_4159, Dermatoscopy showed that the skin lesion was lobular and crumby. The lesion center ... View More
Are there white streaks present in the lesion? Are patterned white streaks present in the skin lesion? 3761_15419 The group with an active phase of the disease displayed through dermoscopy red dots that were congested, enlarged vessels surrounding white rosettes and white streaks on a pinkish-reddish background. ID: 3761_15419, Termed also as “COVID toes”, the lesions were located on acral surfaces, i.e., the... View More
Does the skin lesion display pigmented islands? Are patterned white streaks present in the skin lesion? 2798_2737 The most common dermoscopic features of the 12 pigmented BCCs were: pigmented islands (blue-gray globules and blue-gray ovoid nests). ID: 2798_2737, The most common dermoscopic features of the 12 pigmented BCCs were: pigmented islan... View More
Does the skin lesion show irregular hyperpigmented areas? Are patterned white streaks present in the skin lesion? 1901_21578 Furthermore, the multivariate analysis pointed that there were 5 positive dermoscopic indicators of MIS: irregular hyperpigmented areas. ID: 1901_21578, Furthermore, the multivariate analysis pointed that there were 5 positive dermosco... View More
Do the streaks on the skin lesion follow a linear pattern? Are patterned white streaks present in the skin lesion? 1906_6857 Both conditions can be easily differentiated from each other by the age of onset, by the typical arrangement of nevus comedonicus lesions in a linear streak pattern. ID: 1906_6857, The surrounding skin usually shows classic unmistakable signs of severe actinic dam... View More
Does the lesion contain a variety of colours? Is the lesion melanocytic? 2504_13465 When utilising conventional digital photographs for the analysis of melanocytic and non-melanocytic lesions, the images usually consist of more colours than the dermoscopic images of melanocytic lesions. ID: 2504_13465, Precise segmentation was considered an essential step when using the CADx system f... View More
Are there visible borders between lesion and non-lesion areas? Is the lesion melanocytic? 2504_13465 Without the use of microscopic facilities, there were no definite criteria for defining the true borders between the lesion and non-lesion areas under gross examination. ID: 2504_13465, Precise segmentation was considered an essential step when using the CADx system f... View More
Does the lesion exhibit any form of asymmetry? Is the lesion melanocytic? 210_6581 Accurate diagnosis of melanoma relies on a histopathologic gold standard; thus, aggressive excision of melanocytic skin lesions has been the mainstay of treatment. ID: 210_6581, Melanoma will affect an estimated 73,000 new cases this year and result in 9,000 dea... View More
Can you observe parallel oriented, enlarged blood vessels? Are there vascular morphologies present in the lesion? 2691_26966 Sauermann et al found numerous, horizontal, parallel oriented, enlarged blood vessels. ID: 2691_26966, Blood flow can be observed due to fast moving bright particles inside the vessel l... View More
Are there any distinct morphological characteristics such as macule, plaques, or nodules? Are there vascular morphologies present in the lesion? 2735_22252 At the first visit, patients presenting skin lesions were examined and those diagnosed with “leprosy-like lesions” (macule, plaques or nodules) were eligible to enroll. ID: 2735_22252, Patient inclusion and exclusion criteria and overall workflow until AI data analys... View More
Are there inconsistencies or color changes present in the lesion? Does the lesion adhere to the ABCD dermoscopy rule? 3065_5006 In order to diagnose the medical problems of melanoma lesions, dermatologists directly examine the damaged skin's uniformity, inconsistencies in the borders, and color changes [4]. ID: 3065_5006, On the other hand, the survival rate for the early stages of melanoma is around 95%... View More
Is the diameter of the lesion large? Does the lesion adhere to the ABCD dermoscopy rule? 3302_29097 A number of diagnostic criteria and algorithms have been developed for this purpose, including pattern analysis [4], the ABCD (asymmetry, border, color, diameter) rule [5]. ID: 3302_29097, The use of dermoscopy, a low-cost, noninvasive diagnostic technique based on a han... View More
Does the lesion have irregular vascular patterns? Does the lesion adhere to the ABCD dermoscopy rule? 2181_25241 Major criteria consist of atypical networks, blue-whitish veils, and atypical vascular patterns. ID: 2181_25241, Dermoscopy has been shown to improve significantly the diagnosis of melanocytic le... View More
Do irregular structures appear within the lesion when dermoscopy is used? Does the lesion adhere to the ABCD dermoscopy rule? 157_5201 Most algorithms (e.g., the ABCD rule of dermoscopy [15], the 7-point checklist of dermoscopy [16], or Menzies’ scroring method [17]) use a number of criteria associated with the presence of melanoma as first described for the pattern analysis by Pehamberger et al [18]. ID: 157_5201, More recently dermoscopes that emit polarized light to eliminate skin surface reflec... View More
Does the lesion have atypical networks or blue-whitish veils visible? Does the lesion adhere to the ABCD dermoscopy rule? 2181_25241 Major criteria consist of atypical networks, blue-whitish veils, and atypical vascular patterns. ID: 2181_25241, Dermoscopy has been shown to improve significantly the diagnosis of melanocytic le... View More
Does the lesion have color variations? Can the lesion's edges be clearly defined under dermoscopy? 1515_13585 C is color. ID: 1515_13585, An often-used mnemonic for early signs of melanoma is "ABCDE", where A corresponds... View More
Can subepidermal structures of the lesion be seen? Can the lesion's edges be clearly defined under dermoscopy? 2960_15241 Dermoscopy allows visualization of deeper subepidermal structures. ID: 2960_15241, The immense potential of dermoscopy in diagnosing pigmented lesions of skin and sk... View More
Does the dermoscopy display subsurface skin structures in the epidermis, at the dermoepidermal junction, and in the upper dermis? Are there morphologic features visible under dermoscopy that are not visible to the naked eye? 4857_1590 Dermoscopy is a non-invasive, in vivo technique that allows the visualization of subsurface skin structures in the epidermis, at the dermoepidermal junction, and in the upper dermis. ID: 4857_1590, Dermoscopy is a non-invasive, in vivo technique that allows the visualization of su... View More
Does the lesion show central ulceration-crust? Does the lesion lack round structures in dermoscopy? 176_12779 Dermoscopy can be helpful when we observe skin lesions similar to that of MPXV infection, showing a recurrent and quite specific pattern with central ulceration-crust. ID: 176_12779, However, MPX skin lesions might be difficult to distinguish from other clinically s... View More
Can you observe brown dots in the central area of the lesion? Does the lesion lack round structures in dermoscopy? 3074_3209 Dermoscopy showed a white and brown annular double-track at the periphery and brown dots in the surrounded central area. ID: 3074_3209, Indeed, investigators have described the clinical and dermatoscopic evolution of DS... View More
Can you identify any follicular involvement in the lesion? Does the lesion lack round structures in dermoscopy? 3074_3209 The DSAP lesions of the reported patient also had clinical and dermoscopic features of follicular involvement. ID: 3074_3209, Indeed, investigators have described the clinical and dermatoscopic evolution of DS... View More
Is there a presence of white scaling on the lesion? Does the lesion display exfoliation or white structureless areas? 2905_16280 DLE on glabrous skin showed polymorphous vessels, pink-red background, follicular plugs and white scaling. ID: 2905_16280, A total of 85 lesions from 26 patients (16 women and 10 men; mean age 40.8 ± 11.2 ... View More
Is the lesion area diffuse or concentrated? Does the lesion display exfoliation or white structureless areas? 4857_1646 White structureless areas are a diffuse white pigmentation that does not occupy the entire lesion. ID: 4857_1646, White structureless areas are a diffuse white pigmentation that does not occupy the... View More
Are there linear or dotted vessels visible on the lesion? Does the lesion display exfoliation or white structureless areas? 878_3999 The dermoscopic features of eczema are linear vessels, scattered dotted vessels, and yellow scales. ID: 878_3999, Dermoscopy and reflectance confocal microscopy (RCM) are widely used techniques for ... View More
Does the lesion show signs of exfoliation or surface scale? Does the lesion display exfoliation or white structureless areas? 203_10153 Dermatoscopically there were no blue structures but there was a central red and brown structureless area with radial lines at the periphery in a circumferential distribution. ID: 203_10153, Inspection of the dermatoscopic images presented revealed an asymmetric structurele... View More
Is the lesion symmetric or asymmetric? Does the lesion display exfoliation or white structureless areas? 203_10153 Inspection of the dermatoscopic images presented revealed an asymmetric structureless lesion with the added clue to malignancy of the color blue. ID: 203_10153, Inspection of the dermatoscopic images presented revealed an asymmetric structurele... View More
Are blood vessels visible within the lesion? Do the lesions contain enlarged blood vessels? 2691_26965 Using RCM, cutaneous vascular structures and blood flow can be visualized in real-time. ID: 2691_26965, Although dermoscopy has its indisputable place in the non-invasive diagnosis of sk... View More
Are there vessels of varied sizes and shapes within the lesion? Do the lesions contain enlarged blood vessels? 2736_15964 Dermoscopic examination of the lesion revealed dark-pink and brown diffuse areas overlapped by vessels with varied sizes and shapes, mostly glomerular, dotted and comma-like. ID: 2736_15964, Associated with the atypical honeycomb pattern in the spinous layer, there was a h... View More
Does the lesion show arborizing vessels under dermoscopy examination? Do the lesions contain enlarged blood vessels? 568_29784 Dermoscopy examination highlights a few vascular patters suggestive of BCC, such as arborizing vessels. ID: 568_29784, Dermoscopy examination highlights a few vascular patters suggestive of BCC, but som... View More
Does the lesion show short fine telangiectasia under dermoscopy? Do the lesions contain enlarged blood vessels? 568_29784 Of all the vascular patterns, arborizing vessels and/or short fine telangiectasia are the ones that are the most helpful in the differential diagnosis of BCC. ID: 568_29784, Dermoscopy examination highlights a few vascular patters suggestive of BCC, but som... View More
Are more than two blood vessels visible in the lesion? Are there irregular blood vessels in the lesion? 4745_27717 Maximum intensity projection (MIP) showed that malignant lesions had two or more blood vessels. ID: 4745_27717, The dynamic contrast-enhanced features revealed by DCE-MRI showed that benign brea... View More
Is the lesion under the skin displaying an irregular structureless area? Are there irregular blood vessels in the lesion? 2913_23565 3: pigmented criteria brown or blue‐grey structureless areas, blue‐grey globules, black dots. ID: 2913_23565, 3: pigmented criteria (brown or blue‐grey structureless areas, blue‐grey globules,... View More
Are the blood vessels in the lesion arranged in a disorganized way? Are there blood vessels arranged linearly along the lesion? 4771_19675 In BCC lesions the calibre of the blood vessels showed great variance, ranging from dilated, larger-than-normal vessels to the smallest detectable vessels. In addition, the vessels were arranged in a disorganized way with a multitude of minute vessels, loosing the regularity seen in the un-involved skin. ID: 4771_19675, Analysis was done qualitatively comparing en face images of lesions with adjacent ... View More
Are there dotted vessels located in the reticular spaces on the borders of the lesion? Are there blood vessels arranged linearly along the lesion? 2559_24632 Dotted vessels located in the reticular spaces on the borders of junctional nevi indicate dermal papilla and are not regarded as tumors. ID: 2559_24632, Dotted vessels generally have a high positive predictive value in melanocytic skin... View More
Is the lesion erythematous and scaly? Are there blood vessels arranged linearly along the lesion? 5282_4849 Examination revealed well-defined, erythematous scaly papules and plaques arranged linearly over the lateral border of distal left arm. ID: 5282_4849, Sir,A 70-year-old female presented with occasional mildly pruritic linear lesions o... View More
Does the lesion exhibit dark pigmentation? Does the lesion contain dark spots? 2198_28982 Melanosis is termed as a diffuse or spotted lesion characterized by dark pigmentation on the face, neck, limbs and trunk. ID: 2198_28982, Within these 12 years, 1403 patients were found with cutaneous malignancy among wh... View More
Does the lesion stand out due to its dark appearance? Does the lesion contain dark spots? 4762_25286 The screening examination should usually include two looks, one for any lesion that stands out at all, which should allow detection of changed or ugly duckling lesions, and a second look to identify lesions of any size that stand out because of appearing, even focally, dark. ID: 4762_25286, The screening examination should usually include two looks, one for any lesion tha... View More
Does the lesion appear as a dark-brown or black macule? Does the lesion contain dark spots? 187_22583 Clinically, those lesions present themselves as a dark-brown or black macule that does not allow for a clear distinction between nevus and melanoma because it was not given the time to develop features that make it recognizable. ID: 187_22583, The same is true for nevi “in special sites,” such as acral skin or genitalia, that... View More
Does the lesion show changes in skin texture? Is there a presence of sharp demarcation in the lesion? 5356_33556 Changes in skin texture due to tumor proliferation and a finding of tumor structures in the skin adjacent to the demarcated clinical margin were considered dermoscopic patterns. ID: 5356_33556, Demarcation of surgical margins in a control group patient Dermoscopic demarcation... View More
Is the lesion's demarcation line clear to distinguish? Is there a presence of sharp demarcation in the lesion? 2538_18282 According to the VS classification system, the characteristic M-NBI findings of EGC are a clear demarcation line between non-cancerous and cancerous mucosa. ID: 2538_18282, According to the VS classification system, the characteristic M-NBI findings of EG... View More
Does the lesion feature scales or white follicles? Is there a presence of sharp demarcation in the lesion? 15_18231 it focuses on the dermoscopic presence or absence of 7 features of nonmelanoma tumors: scales, white follicles, erythema, reticular or curved lines, structureless brown color, sharp demarcation. ID: 15_18231, Rather than aiming to the recognition of melanoma-specific criteria, it focuses on t... View More
Does the lesion have distinct and possibly hyperpigmented margins? Is there a presence of sharp demarcation in the lesion? 1547_16904 Vitiligo was defined as depigmented macules and patches that have relatively distinct and possibly hyperpigmented margins present in the lips. ID: 1547_16904, An OML was defined as any abnormal change or any swelling on the oral mucosal surf... View More
Is the lesion slightly raised or depressed? Is there a presence of sharp demarcation in the lesion? 3290_3934 For type I (raised type), the lesion protrudes into the gastric cavity; type II (flat type): the bulge and depression of the lesion are not conspicuous. ID: 3290_3934, For type I (raised type), the lesion protrudes into the gastric cavity; type II (fl... View More
Does the lesion present with pseudopods? Does the lesion present with a network of structures? 2242_15890 In the present study the development of atypical pigment network and pseudopods was observed in both melanomas and dysplastic melanocytic nevi. ID: 2242_15890, In the present study the development of atypical pigment network and pseudopods wa... View More
Does the lesion have a discolored central area? Does the lesion appear macular (flat) or papular (elevated)? 298_13585 The central area is typically discolored, while the periphery blends into normal skin. ID: 298_13585, Signs and symptoms of secondary syphilis include a rash involving the palms and sol... View More
Is the lesion round and firm? Does the lesion appear macular (flat) or papular (elevated)? 3518_12871 Papular lesions: red, raised, firm round nodules with a grey center that may ulcerate. ID: 3518_12871, Macular lesions: flat-to-slightly raised, firm, red lesions with particular predil... View More
Does the lesion have a crusty appearance? Does the lesion appear macular (flat) or papular (elevated)? 160_11869 Crusty sores are no longer contagious once fresh skin has emerged. ID: 160_11869, More lesions will appear on the face and extremities than on the trunk and abdomen ... View More
Are there abrupt cut-offs in any section of the lesion's border? Does the lesion have irregular borders? 1379_9846 The authors used a simple method to measure border irregularity, in which a simple semi-quantitative evaluation method is used to divide the lesion into eight similar parts such that the sharp abrupt cut-off in each part has a score of 1. ID: 1379_9846, The authors used a simple method to measure border irregularity, in which a simple ... View More
Is the convexity of the lesion border less than 1? Does the lesion have irregular borders? 1379_9970 Another plot is drawn in Fig. 16 to depict the distribution of convexity values, where irregular skin lesion borders tend to move away from the value 1 (less convex). ID: 1379_9970, The label column L in Table 2 is manually added and reflects the labeling made by t... View More